The Science
Genetics, chemical exposure in your environment and nutritional deficiencies are some key factors that can impact neurotransmitter production. Once they are out of balance, it's only a matter of time before the nervous system will try to compensate, leading to neurological or psychological symptoms like anxiousness, low mood, ADHD/hyperactivity disorders, sleep disturbances, persistent stress and chronic fatigue. Using a simple urine sample, the Mind & Body Neurotransmitter Test can uncover a potential neurotransmitter imbalance, and based on your results you can begin to implement appropriate diet and lifestyle recommendations that will help to rebalance your mind and body.
What is Measured
Inhibitory Biomarkers
Serotonin, 5-HIAA, GABA, Glycine
Inhibitory (calming) neurotransmitters block or prevent the chemical message from being passed along any farther.
Serotonin: Helps regulate mood, sleep patterns, sexuality, anxiety, appetite and pain. Diseases associated with serotonin imbalance include seasonal affective disorder, anxiety, depression, fibromyalgia and chronic pain.
5-HIAA: A metabolite of serotonin
GABA: The most common inhibitory neurotransmitter of your nervous system, particularly in your brain. It regulates brain activity to prevent problems in the areas of anxiety, irritability, concentration, sleep, seizures and depression.
Glycine: The most common inhibitory neurotransmitter in your spinal cord. Glycine is involved in controlling hearing processing, pain transmission and metabolism
Excitatory Biomarkers
Glutamate, histamine, PEA, dopamine, DOVAC, HVA, norepinephrine, epinephrine, norepinephrine:epinephrine ratio, VMA
Excitatory (energizing) neurotransmitters "excite" the neuron and cause it to "fire off the message," meaning, the message continues to be passed along to the next cell.
Glutamate: Functions as the major excitatory neurotransmitter and metabolic fuel throughout the body. Clinically, high glutamate is suspected in anxiety, autism spectrum disorder, depression and sleep issues and clinically low glutamate is implicated in depression, chronic fatigue, lack of concentration, low energy levels, and sleep disturbances.
Histamine is a neurotransmitter and immunomodulator. It regulates body functions including wakefulness, feeding behavior and motivation.
PEA: Serves as a biomarker for ADHD.
Dopamine: Serves as the reward and pleasure center in the brain, and messenger of the sympathetic nervous system in the periphery.
DOPAC and HVA: Metabolites of dopamine.
Norepinephrine (noradrenaline) and epinephrine(adrenaline): Regulate the "fight or flight" response to fear and stress.These neurotransmitters stimulate your body's response by increasing your heart rate, breathing, blood pressure, blood sugar and blood flow to your muscles, as well as heighten attention and focus to allow you to act or react to different stressors.
Ratio: Norepi/Epi. Having too much or too little of either can have noticeable effects on your health. An elevated ratio of Norepi/Epi may be consistent with poor conversion of norepinephrine to epinephrine.
VMA: A metabolite of norepinephrine and epinephrine.